Arev, Marija and Janevik-Ivanovska, Emilija and Apostolova, Paulina and Dzodic, Predrag (2017) Freeze dried kit formulation of trastuzumab-immunoconjugates. In: 17th CEEPUS Symposium and Summer School on Bioanalysis.
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Abstract
Trastuzumab is a humanized anti-HER2 monoclonal antibody used for therapy of metastatic breast cancer. Conjugated antibodies with toxins, drugs and radionuclides, provide high hope for development of cancer-specific cytotoxic reagents. The formulation of stable immunoconjugates with a bifunctional chelators (BFCA) is required in order to obtain successful radiolabeling. The aim of this examination was to development a stable freeze dried trastuzumab immunoconjugates with BFCA p-SCN-Bn-DTPA, p-SCN-Bn-DOTA, 1B4M-DTPA.
| Item Type: | Conference or Workshop Item (Poster) |
|---|---|
| Subjects: | Medical and Health Sciences > Other medical sciences |
| Divisions: | Faculty of Medical Science |
| Depositing User: | Marija Arev |
| Date Deposited: | 24 Aug 2017 08:01 |
| Last Modified: | 26 May 2023 10:06 |
| URI: | https://eprints.ugd.edu.mk/id/eprint/18085 |
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