Quality management in hospitals: analysis of the prescribing practice of cardiovascular medicines

Stoimenova, Assena and Savova, Alexandra and Georgieva, Svetla and Angelovska, Bistra and Petrova, Guenka (2014) Quality management in hospitals: analysis of the prescribing practice of cardiovascular medicines. World Journal of Pharmacy and Pharmaceutical Sciences, 3 (3). pp. 93-102. ISSN 2278 – 4357

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Abstract

The goal of this study is to analyse the prescribing practice and risk of
drug related errors in a Cardiology clinic of University Hospital. Semistructured
open-ended interview aiming to reveal the risk of potential
errors was performed with physicians, nurses, pharmacists, and
hospital managers. Observational analysis of 915 prescriptions,
prescribed by the physicians in two cardiology departments was
conducted. Prescribing practice was evaluated by the means of its
complexity, frequency of prescribing of particular pharmacology
groups, and the related costs. Most often gaps detected in prescribing
and dispensing of medicinal products were associated with missing or
incorrect dosages, and unspecified quantity. Our analysis showed
preference to combination therapies. Monotherapy was given only in 24.82% of the acute
cases treated and in 24% of the cases treated in the internal ward. Two medicinal products
were identified in 24.48% of the prescriptions (intensive care unit) and in 19.24% of the
prescriptions from the internal ward. The most prescribed medicinal products were bisoprolol
and glyceryl trinitrate in a combination. Approximately 45% of the patients were prescribed
up to 3 medicinal products.The increase of therapy complexity leads to increase of
probability for drug-drug interactions and nearly 30% of prescriptions were evaluated as
potentially risky for interactions. The relative shares of potentially risky combinations vary
from 4% to 32% out of all prescriptions reviewed. The likelihood of drug-related problems in the observed Cardiology clinic was determined as high but no practice for recording of ADRs was found in place.

Item Type: Article
Subjects: Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Medical Science
Depositing User: Bistra Angelovska
Date Deposited: 07 Apr 2014 12:46
Last Modified: 07 Apr 2014 12:47
URI: https://eprints.ugd.edu.mk/id/eprint/9712

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