Hyperkeratosis of the Oral Mucosa – a case report

Stojanova, Irena and Stojanovski, Dime and Cara, Nart and Markovska Arsovska, Mirjana and Mencheva, Zaklina and Trajculeski, Stavre and Cvetanoski, Ognen (2026) Hyperkeratosis of the Oral Mucosa – a case report. In: Dental Naissa, International dental congress, 18-21 Sept 2025, Nis, Serbia.

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Abstract

Introduction: Hyperkeratosis of the oral mucosa is a condition characterized by excessive thickening of the keratin layer of the mucous membrane, most often as a result of chronic irritation or injury. Although not typically considered serious, this condition can be caused by various factors such as smoking, alcoholism, or poor oral hygiene. Aim: Aim of this article is to present a clinical case of hyperkeratosis of the oral mucosa in a 23-year old female patient. Hyperkeratosis can be a precursor to malignant diseases. A histopathological biopsy of the oral mucosa is necessary for a definitive diagnosis. Material and methods: A sample of the oral mucosal lesion was sent for histopathological analysis to the Institute of Pathology. Results: The biopsy section showed hyperkeratotic stratified squamous epithelium with acanthotic thickening, indicating hyperkeratosis. Conclusion: Early diagnosis and appropriate
treatment of this condition are important to prevent serious complications.
Key words: hyperkeratosis, keratin, irritations, injuries, oral mucosa

Item Type: Conference or Workshop Item (Poster)
Uncontrolled Keywords: hyperkeratosis, keratin, irritations, injuries, oral mucosa
Subjects: Medical and Health Sciences > Clinical medicine
Divisions: Faculty of Medical Science
Depositing User: Mirjana Markovska Arsovska
Date Deposited: 02 Mar 2026 09:21
Last Modified: 02 Mar 2026 09:21
URI: https://eprints.ugd.edu.mk/id/eprint/38112

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