Therapeutical procedures in patients with trigeminal neuralgia - literature review

Susak, Zoran and Popovski, Vladimir and Mitikj, Jovana and Veljanovski, Darko (2020) Therapeutical procedures in patients with trigeminal neuralgia - literature review. Macedonian Dental Review, 43 (2). pp. 60-67. ISSN 2545-4757

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Abstract

Trigeminal neuralgia (ТN) is the most common pathological condition of the cranial nerves and the most common cause of pain in the orofacial region. More and more
literary data indicate that a in significant number of patients, ТN is caused by compression on the root of the trigeminal nerve, close to its entry into the pons in the
aberrant arterial or venous loop leading to pathohistological changes in the nerve while in most of the same, the etiological factor for the pathology of TN remains a
mystery. Numerous medical and surgical procedures are available, usually without a number of randomized clinical trials and studies of placebo-controlled groups. As
a result, most patients experience refractory pain, which has a significant effect on reducing their quality of life. It is still unclear how available treatment methods can
be best used. Medical treatment consists of anticonvulsant drugs, muscle relaxants and neuroleptic agents, alternative treatments with botulinum toxin. In patients
resistant to drug therapy, promising i.е. recommended surgical procedures include microvascular decompression, gamma-knife surgery, and percutaneous techniques
of the Gasser ganglion. In this paper we will present a systematic review of the literature and investigate the outcome of different types of therapeutic procedures in
patients with trigeminal neuralgia. Keywords: Trigeminal neuralgia, anticonvulsant drugs, pain.

Item Type:	Article
Subjects:	Medical and Health Sciences > Other medical sciences
Divisions:	Faculty of Medical Science
Depositing User:	Zoran Susak
Date Deposited:	20 May 2024 11:59
Last Modified:	20 May 2024 11:59
URI:	https://eprints.ugd.edu.mk/id/eprint/34098

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