Evaluation of topical preparations of meloxicam

Drakalska, Elena and Angelovska, Bistra (2022) Evaluation of topical preparations of meloxicam. Knowledge-International Journal, 55 (4). pp. 749-754. ISSN 2545-4439

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Abstract

Aim of the study: Meloxicam is a non-steroidal, anti-inflammatory medicine that exhibits highly potent
analgesic, antipyretic activity indicated for pain in patients with rheumatoid arthritis, osteoarthritis etc. Despite the
fact that this medicine possesses some COX-2 selectivity over COX-1, it is not considered as COX-2 inhibitor by
FDA. Compared with other NSAID, meloxicam is relatively safer, but unfortunately is associated with gastrointestinal
adverse effects. Currently commercial forms of meloxicam are tablets, oral suspension and injections. An
intriguing strategy to overcome these limitations is formulation of topical dosage forms for transdermal delivery.
Present study reports a detail review of data from clinical studies of different formulations of topical meloxicam,
methods of preparation and characterization of their structure, the influence of various parameters on the stability and the market’s patented formulations by now.

Item Type:	Article
Subjects:	Medical and Health Sciences > Other medical sciences
Divisions:	Faculty of Medical Science
Depositing User:	Elena Drakalska
Date Deposited:	30 Jan 2023 12:34
Last Modified:	30 Jan 2023 12:34
URI:	https://eprints.ugd.edu.mk/id/eprint/31018

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