Impact of symptom severity score and type of treatment on quality of life in patients with benign prostatic hyperplasia

Sofronievska, Maja and Ivchev, Jovan and Stojanoski, Ivica (2022) Impact of symptom severity score and type of treatment on quality of life in patients with benign prostatic hyperplasia. Knowledge – International Journal, 55 (4). pp. 1-30. ISSN 2545 – 4439

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Abstract

Benign prostatic hyperplasia (BPH) is the fourth most common disease in the male population aged over 50 years which results in lower urinary tract symptoms (LUTS). These symptoms lead to affect patients' quality of life (QoL) differently. Quality of life (QoL) refers to the subjective perception of a patient`s well-being in terms of physical, psychological, and socioeconomic aspects. Aging and worsening LUTS/BPH are contributing factors to decreased QoL. Several medicament options that include alpha-blockers and 5 alpha-reductase inhibitors as a "gold" standard, are available for LUTS/BPH treatment. This paper aims to evaluate the effects of pharmacological treatments used to treat LUTS /BPH in daily practice and to allow a comparison of results between treatments. We evaluated 250 patients with BPH using the International Prostate Symptom Score (IPSS) questionnaire, including the eighth question on quality of life concerning the severity of symptoms and the type of drug therapy with which they were treated. When analyzing the results, we concluded that patients with less pronounced symptoms of the disease have a better quality of life (p<0.05), while those patients with more severe symptoms and those who have the appearance of side effects from the therapy have a worse quality of life. (p<0.05). In conclusion, we provide additional evidence of the impact of two different medicament strategies for BPH treatment on patients' QoL to help further inform decision-making regarding treatment strategies in this patient population. A holistic approach is needed in the management of BPH, leading to better QoL in BPH patients.

Item Type:	Article
Subjects:	Medical and Health Sciences > Clinical medicine Medical and Health Sciences > Health sciences
Divisions:	Faculty of Medical Science
Depositing User:	Maja Sofronievska
Date Deposited:	26 Dec 2022 12:37
Last Modified:	26 Dec 2022 12:37
URI:	https://eprints.ugd.edu.mk/id/eprint/30791

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