Abnormal uterine bleeding as a predictor for endometrial abnormalities, quick diagnosis of premalignant and malignant states and the impact of various risk factors

Morarcalieva-Chockova, Anita and Nakova, Marina and Nikova, Petranka and Chochkov, Blaze and Velickova, Nevenka and Georgiev, Dimitar (2022) Abnormal uterine bleeding as a predictor for endometrial abnormalities, quick diagnosis of premalignant and malignant states and the impact of various risk factors. Academic Medical Journal, 2 (2). pp. 78-84. ISSN 2671-3853

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Abstract

Approximately 30% of women will experience abnormal uterine bleeding (AUB)
during their lifetime. It is a common medical problem, with a direct influence on women's
quality of life, utilization of health care resources, and costs.
The aim of this study was to analyze the histopathological findings of the samples
from dilatation and curettage (D&C) in patients with abnormal uterine bleeding and to
determine the presence of certain risk factors (age, obesity, hypertension, diabetes, parity) in
the examined groups.
This was a prospective study including a total of 77 patients from the Department of
Gynecology and Obstetrics in PHI General Hospital Gevgelija, who underwent D&C in 2021.
Data were collected through interviews and analysis of findings from histopathological
analyses of samples obtained by D&C. The following anamnestic data were analyzed: age,
parity, history of hypertension and diabetes. Weight and height were measured in all patients.
The most common pathological change of the endometrium was endometrial polyp.
The second most common histopathological diagnosis in premenopausal women was
anovulatory bleeding vs. menopausal women who were secondly frequent diagnosed with
endometrial hyperplasia. Gynecological cancers were more common in menopausal age.
Various anamnestic factors were differently related to various histopathological diagnoses.
All patients that report abnormal uterine bleeding are diagnosed with endometrial
abnormalities by TVUS and should undergo D&C for quick diagnosis of premalignant and
malignant states of the genital tract. By reducing body weight, regulating hypertension and
diabetes, the risk of the most severe pathological diagnosis is reduced.

Item Type:	Article
Subjects:	Medical and Health Sciences > Basic medicine Medical and Health Sciences > Clinical medicine
Divisions:	Faculty of Medical Science
Depositing User:	Nevenka Velickova
Date Deposited:	23 Dec 2022 13:09
Last Modified:	23 Dec 2022 13:09
URI:	https://eprints.ugd.edu.mk/id/eprint/30737

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