Cyclic Voltammetry Makes Clear Distinction between Decomposition of Enzymatic Adsorbed Film and the Chemical Inactivation of Initial Redox Enzymatic Form in Protein-Film Voltammetry

Gulaboski, Rubin (2022) Cyclic Voltammetry Makes Clear Distinction between Decomposition of Enzymatic Adsorbed Film and the Chemical Inactivation of Initial Redox Enzymatic Form in Protein-Film Voltammetry. [Dataset] (Submitted)

Text (MATHCAD File for simulation ECinhibition mechanism in Protein-Film Voltammetry) Cyclic ECihnibition in PFV sept 2022 gulaboski.pdf - Supplemental Material Download (512kB)

Abstract

Loss of the material from adsorbed protein-film and the enzymatic inhibition of initial redox form of electrochemically active enzyme are events that show quite similar voltammetric patterns under conditions of protein-film voltammetry. We give in this work a MATHCAD File that enables simulation of cyclic voltammograms of a protein-film mechanism in which the initial redox enzymatic form is involved in an electrochemical transformation and in parallel irreversible reaction of deactivation. While we give plenty of simulated voltammograms of this mechanism, with the formulas provided in the MATHCAD file one can make simulations of this mechanism in cyclic voltammetry, and can get benefit of calculated voltammograms in distinguishing the current mechanism from protein loss. Hints are given that allow estimation of kinetics of both rate parameters involved in this mechanism. Model is solved for the first time from our group under voltammetric conditions.

Item Type:	Dataset
Subjects:	Medical and Health Sciences > Basic medicine Natural sciences > Chemical sciences Natural sciences > Physical sciences
Divisions:	Faculty of Medical Science
Depositing User:	Rubin Gulaboski
Date Deposited:	02 Sep 2022 09:52
Last Modified:	02 Sep 2022 09:52
URI:	https://eprints.ugd.edu.mk/id/eprint/30166

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