Tissue Fluorescence Imaging for Quick Non-Invasive Diagnosis in Oral and Maxillofacial Surgery

Nikolovski, Bruno and Radojkova-Nikolovska, Vera and Dimova, Cena and Popovska, Mirjana and Ristovska, Stevica and Belazelkovska, Ana and Popovic-Monevska, Danica (2021) Tissue Fluorescence Imaging for Quick Non-Invasive Diagnosis in Oral and Maxillofacial Surgery. Journal of Morphological Sciences, 4 (3). pp. 1-13. ISSN 2545-4706

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Abstract

Significant vital functions take place in the oral cavity and oropharynx, primarily mastication, as the initial function of the gastrointestinal system, swallowing, respiration and speech. All these vital biological functions can be endangered, ie aggravated, and even disabled by the appearance of neoplasms in that anatomical space. In the maxillofacial region, neoplasms can originate from a variety of tissues, from the mucous membranes of the oral cavity to the jaws, salivary glands, and even tumors of odontogenic origin. However, the most common tumor in the oral cavity is squamous cell carcinoma (OSSC), which originates fromthe oral mucosa.To determine the accuracy, sensitivity (Se)andspecificity (Sp) of the Velscope screening method in the detection of premalignant and initial malignant lesions compared to the gold standard surgical biopsy.The study group consisted of 60 patients divided into two groups. The first group was formed by 30 patients with potentially malignant oral lesions (PML). Another 30 patients withpreliminarydiagnosis -oral cancer (OC) were included in the second group of examinees. The high sensitivity value of 92.86% and the accuracy of the method of 86.67% largely confirm the reliability and efficacy of the Velscope method in patients with highly suspected oral cancer lesions (OC), significantly more, comparing to the group of premalignant lesions. Key words: Velscope, oral cancer, premalignant lesions, tumor.

Item Type:	Article
Subjects:	Medical and Health Sciences > Basic medicine Medical and Health Sciences > Clinical medicine Medical and Health Sciences > Health sciences Medical and Health Sciences > Other medical sciences
Divisions:	Faculty of Medical Science
Depositing User:	Cena Dimova
Date Deposited:	11 Feb 2022 07:43
Last Modified:	11 Feb 2022 07:43
URI:	https://eprints.ugd.edu.mk/id/eprint/29407

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