Serous adenofibroma of the fallopian tube with coexistent ectopictubal pregnancy

Kubelka-Sabit, Katerina and Filipovski, Vanja and Dimova, Biljana and Trajkova, Kornelija and Jasar, Dzengis (2020) Serous adenofibroma of the fallopian tube with coexistent ectopictubal pregnancy. Virchows Archiv. ISSN 1432-2307 (electronic version) Journal no. 428

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Abstract

Background & objectives:Serous adenofibromas of the fallopian tubeare rare tumours considered to be analogous to their counterparts in theovary. They are usually small and incidental finding during surgery.We present a 34-year old patient withprevious history of uterinebleeding.Methods:The patient was misdiagnosed in another institution as miscar-riage. Due to persistent elevation of the HCG serum levels (from 2350 IU/L to 5980 IU/L), ultrasound examination was performed, which led tosuspected left ectopic tubal pregnancy. Five days after receiving metho-trexate, the patient was again admitted to the hospital with abdominal painand vomiting. Left fallopian tube was surgically removed.Results:Histopathologic examination confirmed ruptured ectopic tubalpregnancy in the isthmic portion. Small, 4 mm firm yellow nodule wasattached to the fimbriae. On microscopic examination, the nodule waswell-demarcated and consisted of intersected fibroblasts and hyalinizedcollagen bundles with few slit-like or cystic spaces covered with benignepithelium. Stromal cells were focally positive for inhibin and CD10,whereas epithelial cells coexpressed vimentin and cytokeratin 7, as wellas oestrogen receptor.Conclusion:Ectopic pregnancy in this patient might have potentiallybeen caused by the presence of tubal adenofibroma. Even though onlyfew cases of coexistent ectopic tubal pregnancy and serous adenofibromaof the fallopian tube have been published in the literature, ectopic tubalpregnancy associated with other benign tumours, such as adenomatoidtumour, leiomyoma or mature cystic teratoma have been reported. Thesetumours might lead to partial obstruction of the fallopian tube or mimicectopic pregnancy.

Item Type:	Article
Impact Factor Value:	4.064
Uncontrolled Keywords:	Serous adenofibroma, coexistent ectopic pregnancy
Subjects:	Medical and Health Sciences > Basic medicine Medical and Health Sciences > Clinical medicine Medical and Health Sciences > Health sciences Medical and Health Sciences > Other medical sciences
Divisions:	Faculty of Medical Science
Depositing User:	Vanja Filipovski
Date Deposited:	06 Dec 2021 08:22
Last Modified:	13 Jan 2023 10:57
URI:	https://eprints.ugd.edu.mk/id/eprint/28671

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