The role of Crystal Engineering in designing functional materials (perspective for Pharmaceutical cocrystals)

Cvetkovski, Aleksandar and Drakalska, Elena and Duvlis, Sotirija and Angelovska, Bistra (2021) The role of Crystal Engineering in designing functional materials (perspective for Pharmaceutical cocrystals). In: International Scientific Conference on the “Actual problems of the natural science" dedicated to 98th anniversary of National leader heydar Aliyev, 06-07 May 2021.

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Abstract

Crystal engineering cover the most recent advances in process-dependent properties of functional materials, concerning not only correlations between crystal growth process and characterization, but also growth process design strategy for their enhanced functional and smart properties to be applied in various type of functional materials exhibiting interesting optical, electronic, magnetic, catalytic and mechanical properties that offer wide range of their application in energy, healthcare, electronics, engineering and catalysis. In the past decade, pharmaceutical cocrystals have demonstrated significant promise in their ability to modify the physicochemical and pharmacokinetic properties of drug substances, such as the solubility and dissolution rate, bioavailability, particle morphology and size, tableting and compaction, melting point, physical form, biochemical and hydration stability, and permeability. Manipulating on the noncovalent interactions, established in controlled conduction of processing the solid phases, it is possible to alter the packing motifs that consequently lead to macroscopic solid phases with modulated properties comparing to native substance.
Keywords: Crystal engineering, molecular recohnition, pharmaceutical multicomponent solids

Item Type:	Conference or Workshop Item (Paper)
Subjects:	Medical and Health Sciences > Basic medicine Engineering and Technology > Chemical engineering Natural sciences > Chemical sciences Engineering and Technology > Materials engineering Engineering and Technology > Nano-technology
Divisions:	Faculty of Medical Science
Depositing User:	Aleksandar Cvetkovski
Date Deposited:	09 Sep 2021 08:32
Last Modified:	09 Sep 2021 08:32
URI:	https://eprints.ugd.edu.mk/id/eprint/28432

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