Vitlarova, Jordanka and Kamcev, Nikola and Dejanova, Vesna and Shorova, Meri (2010) Use of leucodepleted red blood cell concentrates-our 10th year experience. In: Vox Sanguinis - International Journal of Transfusion Medicine, 26 June - 01 July 2010, Berlin, Germany.
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Abstract
Introduction: The removal of the leucocites with the help of filtration improves the quality of red blood cell concentrates, with which the risk of apperance of post-transfusion non haemolitic febrile reactions, aloimunisation, immunosupression, post operative infections, virus contamination (CMV, HTLV), bacteria contamination has been minimized.
Aim: To show the benefit from the use of red blood cell concentrates, poor with leucocites produced with the help of filtration in pacients chronically dependable from transfusion, treated in Daily transfusion hospital.
Methods: In the last ten years in our Daily hospital 816 patients from Stip and from the municipalites from the eastern part of R.Macedonia, have been treated and they have needed blood transfusion once to twice per month, suffering from Talassemia major, Sy.myelodisplasticum, Leucosis lymphatica chr. and malignant disease post operatively, chemiotherapy and radiotherapy. The blood units (450 ml) were donated by voluntary repeated blood donors and the some ones were separated in period of 10-12 hours. The obtained red blood cell concentrates has been filtrated in period of 2-3 days and has been immediately used after this process. Filters for preparation of leucodeplated red blood cell concentrates have been used, prodused by the firms TERUMO-IMUGARD III-RC and PALL-PURECELL RN. The procedure has been done manualy by gravitation. The filtration time is from 18-20 min. The blood samples for analyses have been taken from the system before and after the filter and have been made at the Clinical chematologic laboratory. The following chematologic parameters have been determined: number of Er, Le, Tr and level of Hb and Hct.
Results: With the use of these filters, red blood cell concentrates poor with leucocites for about 99-99,9 % have been produced with which post-transfusion side effects of allogenic leucocites have been prevented. The therapy effect is also important because the number of Er, Hb and Hct remain almost unchanged in the unit of filtrated blood.
| Item Type: | Conference or Workshop Item (Poster) |
|---|---|
| Subjects: | Medical and Health Sciences > Clinical medicine |
| Divisions: | Faculty of Medical Science |
| Depositing User: | Nikola Kamcev |
| Date Deposited: | 21 Jan 2020 14:23 |
| Last Modified: | 21 Jan 2020 14:23 |
| URI: | https://eprints.ugd.edu.mk/id/eprint/23271 |
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