Petrov, Andrej and Pljakoska, Vesna (2015) Pityriasis rubra pilaris. In: European Handbook of Dermatological Treatments. Springer-Verlag Berlin Heidelberg, Germany, pp. 753-756.
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Abstract
Key Points
• Pityriasis rubra pilaris (PRP) is a chronic
papulosquamous disorder of keratiniza-
tion. The etiology is unknown. PRP
shows similarities with psoriasis, but it
is a distinct disease.
• According to Griffi ths, there are six
types of PRP. It appears in adults but
also in a juvenile form. It typically
affects extensor parts of the body, start-
ing usually from the face. Typical lesion
is hyperkeratotic papule. Spearing
islands of the non-affected skin are a
pathognomonic sign. After some time,
salmon-like discoloration of the skin
occurs. Palmoplantar keratoderma is
almost always present.
• Histology is not confi rmatory.
• PRP should be distinguished from psoria-
sis and other papulosquamous disorders.
• Treatment is topical or systemic. Retinoids
are fi rst-line treatment. Biologics are a
new class of available medications for the
treatment of PRP, basically used with suc-
cess in psoriasis.
| Item Type: | Book Section |
|---|---|
| Subjects: | Medical and Health Sciences > Clinical medicine |
| Divisions: | Faculty of Medical Science |
| Depositing User: | Andrej Petrov |
| Date Deposited: | 13 Dec 2017 14:09 |
| Last Modified: | 13 Dec 2017 14:09 |
| URI: | https://eprints.ugd.edu.mk/id/eprint/18642 |
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