Hepatitis B and hepatitis C viral infections, importance, microbiological diagnosis and incidence in Shtip, Republic of Macedonia

Dimik, Ivana and Taleski, Vaso and Simjanovska, Liljana (2017) Hepatitis B and hepatitis C viral infections, importance, microbiological diagnosis and incidence in Shtip, Republic of Macedonia. International Journal Scientific Papers, 16.3. pp. 1081-1084. ISSN 1857-923X

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Abstract

Liver inflamation may be caused by various factors. Infectious agents as most important factors includes: viruses, bacteria and parasites. Most frequent infective hepatitis worldwide are viruses: Hepatitis A, B, C, D and E.
Diagnosis is performed on the basis of symptoms and signs of the patients, anamnesis, laboratory testing, CT and MR and liver biopsy.
Laboratory (serologic) tests includes biochemical tests of blood, detection of enzymes (ALT, AST), detecting of Hepatitis B markers (antigens: HBs, HBc, HBe and antibodies: anti HBs, anti HBc and anti HBe), and fro Hepatitis C: anti HCV antibodies. Detecting of viral DNA for Hepatitis B and viral RNA for Hepatitis C is of great importance, using PCR (Polymerase Chain Reaction).
During period from 2010 to 2015 година, in municipality of Sthip, Republic of Macedonia, from total examined 5149 persons, positive results were for Hepatitis B infections in 171 (3,3 %), from which 97 (56,7 %) male and 74 (43,3 %) female persons. During same period, from a total of 3253 examined persons for Hepatitis C infections, 56 (1, 7 %) had positive results.
From 38 registered addicts three were positive for Hepatitis B (8, 6 %), 32 for Hepatitis C (91, 4 %), and three positive for both (Hepatitis B+C). From 350 prisoners of prison in Sthip, 35 (10%) were positive for Hepatitis C. In the Centre for dialysis in Sthip, from 51 patients, 18 were detected positive for Hepatitis B and 18 positive for Hepatitis C and 15 negative for both infections.

Key words: Hepatitis B, Hepatitis C, diagnosis, incidence, treatment.

Item Type: Article
Subjects: Medical and Health Sciences > Clinical medicine
Medical and Health Sciences > Health sciences
Divisions: Faculty of Medical Science
Depositing User: Vaso Taleski
Date Deposited: 23 May 2017 11:12
Last Modified: 23 May 2017 11:12
URI: https://eprints.ugd.edu.mk/id/eprint/17799

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