Velickova, Nevenka and Milev, Mishko and Ruskovska, Tatjana and Petrova, Biljana (2015) Cytogenetic abnormalities in lymphocytes evaluated with micronucleus assay in medical personnel occupationally exposed to ionizing radiation. Genetika, 47 (3). pp. 927-939. ISSN 1820-6069
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Abstract
The aim of this study was to evaluate the genotoxicity of ionizing radiation on medical personnel using the micronucleus assay and to determine the human health risk. Paired Student’s t-test shows significant statistical difference between the total number of binucleated (BN) cells with micronuclei within the two groups (exposed and control) (t=6,812; p<0,05). The mean of MN frequencies in the exposed group increased in comparison with the mean of MN frequencies in the control group. The formation of small and large micronuclei indicates that medical personnel who are exposed on radiation in their work place, have a chromosomal instability and a risk of cancer.
Key words: micronucleus, lymphocytes, genotoxicity, ionizing radiation, cancer
| Item Type: | Article |
|---|---|
| Subjects: | Medical and Health Sciences > Basic medicine |
| Divisions: | Faculty of Medical Science |
| Depositing User: | Nevenka Velickova |
| Date Deposited: | 22 Dec 2015 14:24 |
| Last Modified: | 22 Dec 2015 14:24 |
| URI: | https://eprints.ugd.edu.mk/id/eprint/14666 |
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