Еvidence based clinical guidelines as a potential for improvement of the newborn infants patient safety

Zisovska, Elizabeta and Slaveska-Raichki, Renata and Nlcha, Vasilka (2014) Еvidence based clinical guidelines as a potential for improvement of the newborn infants patient safety. In: Prvi hrvatski kongres klinicke farmacije, 10-12 Apr 2014, Zagreb, Croatia.

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Abstract

The greatest challenge to the prescribing physician is the newborn infants. There are many reasons for this issuesuch as marked changes in maturation that cause different drug-receptor reaction over the maturation period; differences in pharmacokinetics and pharmacodynamics; narrow therapeutic index; risk from diseases not seen in other subsets of pediatric population and impossibility to scale down information; lack of appropriate information and lack of licensed medicines on the global market. Possible reasons for the knowledge gap in this area lay in ethical concerns, limited populations for certain diseases, difficulties in conducting trials in neonates, lack of infrastructure, errors in dose calculations limited marketing potential compared to adults, etc.

Item Type:	Conference or Workshop Item (Lecture)
Subjects:	Medical and Health Sciences > Clinical medicine
Divisions:	Faculty of Medical Science
Depositing User:	Elizabeta Zisovska
Date Deposited:	13 Jul 2015 14:17
Last Modified:	06 Aug 2015 09:34
URI:	https://eprints.ugd.edu.mk/id/eprint/13625

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