Bosevski, Marijan and Peovska, Irena and Maksimovic, Jelena and Vavlukis, Marija (2006) Prognostic utility of carotid ultrasound and cardiac SPECT imaging in coronary artery bypass patients. Nuclear Medicine Review, 9 (1). pp. 12-17. ISSN 1506-9680
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Abstract
BACKGROUND: The aim of our study was to evaluate the role
of myocardial perfusion imaging (MPI) and common carotid
artery intima-media thickness (CCA IMT) in the prognosis
of patients with coronary artery disease referred for coronary artery
bypass surgery (CABG) in a newly made prognostic model.
MATERIAL AND METHODS: 63 patients (age 60.36 ± 8.28
years) with angiographically established coronary artery disease
referred for CABG were evaluated for: age, smoking, family
disposition, dyslipidaemia, arterial hypertension, obesity,
diabetes mellitus, previous myocardial infarction and revascularization.
Patients underwent nitrate enhanced Gated SPECT
myocardial perfusion imaging, with 17-segment analysis for calculation
of perfusion scores and viability index. Common carotid
artery IMT was measured by B-mode ultrasound. Patients were
followed for cardiovascular events 12 months after CABG.
RESULTS: The obtained data reported mean values of left ventricular
ejection fraction (LVEF) 46.2 ± 14.4%, viability index
0.76 ± 0.55, SRS 17.76 ± 13.81 and summed nitrate score
12.89 ± 10.36. Ultrasound detected CCA IMT 0.90 ± 0.24 mm, with increased value in 67.2% and presence of carotid plaques
in 27.1% of pts. We registered 14 events and 8.8% mortality rate.
Multiple regression modelling showed bilateral carotid plaque
presence as a predictor of total events. Viability index and CCA
IMT have been found as independent death predictors.
CONCLUSIONS: Myocardial perfusion viability index and CCA
IMT are predictors, independently associated with prognosis
of patients referred for CABG.
| Item Type: | Article |
|---|---|
| Subjects: | Medical and Health Sciences > Clinical medicine |
| Divisions: | Faculty of Medical Science |
| Depositing User: | Marija Vavlukis |
| Date Deposited: | 29 Jun 2015 14:31 |
| Last Modified: | 29 Jun 2015 14:31 |
| URI: | https://eprints.ugd.edu.mk/id/eprint/13459 |
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