Design of Feasibility Study for the Establishment of 89Zr Production – Tailored Approach to Introduce New Radiopharmaceuticals in a Developing Country

Kolevska, Katerina and Cocevska, Maja and Atanasova, Marija and Velickovska, Maja and Jolevski, Filip and Angelovska, Bistra and Ugrinska, Ana (2023) Design of Feasibility Study for the Establishment of 89Zr Production – Tailored Approach to Introduce New Radiopharmaceuticals in a Developing Country. In: International Symposium on Trends in Radiopharmaceuticals (ISTR-2023), 17-21 Apr 2023, Vienna, Austria.

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Abstract

Establishing radiopharmaceutical production in a developing country is challenging, mainly in the
economic aspect. A feasibility study provides an objective insight into many aspects of the
feasibility of the idea of introducing new radiopharmaceutical. The feasibility study for
establishing production of 89Zr is designed to include preliminary analysis, market research,
technical feasibility analysis, economic analysis, review and analysis of all data, and feasibility
conclusion. The preliminary analysis comprises a review of the application of 89Zr�radiopharmaceuticals in clinical trials and a review of the cancer statistics on a national level. The
technical feasibility determination is based on the analysis of the technical capacities of the
production site – University Institute of Positron Emission Tomography. The economic feasibility
estimation comprehends financial and pharmacoeconomic analysis, which aims to assess the
justification for implementing a new radiopharmaceutical in clinical practice. For this purpose, a
cost-effectiveness analysis is performed. 89Zr-trastuzumab is selected as a subject of the
pharmacoeconomic estimation, based on the results of the preliminary analysis: 89Zr-trastuzumab
is one of the most common 89Zr-radiopharmaceuticals in clinical trials, and on the national level
the breast cancer is the most common malignancy and the most common cause of death from
cancers in the female population

Item Type:	Conference or Workshop Item (Speech)
Subjects:	Medical and Health Sciences > Other medical sciences
Divisions:	Faculty of Medical Science
Depositing User:	Marija Atanasova
Date Deposited:	28 Jun 2024 09:19
Last Modified:	28 Jun 2024 09:19
URI:	https://eprints.ugd.edu.mk/id/eprint/34369

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