Theory of two-step electrode transformations coupled with chemical equilibria relevant to electrochemistry of lipophilic redox enzymes studied under conditions of square-wave voltammetry

Gulaboski, Rubin (2021) Theory of two-step electrode transformations coupled with chemical equilibria relevant to electrochemistry of lipophilic redox enzymes studied under conditions of square-wave voltammetry. . (Unpublished)

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Abstract

Protein-film voltammetry is recognized as a simple but useful technique that can provide access to the electrochemical features of various lipophilic redox enzymes. The so-called “two-step electrode mechanisms” pare related to the redox chemistry of relevant enzymatic systems whose redox transformation occurs in two consecutive steps. In our recent works we published several theories of two-step electrode mechanisms, in which the electron transfer steps were associated with preceding, follow up or regenerative chemical step. In this work, we present some of the major achievements of the protein-film voltammetry of two-step electrode mechanisms coupled with various chemical equilibria. We also provide the readers several hints on how to use methodologies for the determination of thermodynamic and kinetic parameters relevant to two-step protein-film mechanisms. The considered mechanisms are applicable to many lipophilic redox proteins and enzymes that undergo electrochemical transformations in more than one successive electron steps. Such examples exist by proteins containing quinone moiety and some polyvalent ions of transition metals as redox active sites. We provide the readers original MATHCAD Files for some systems, which can be used to simulate square-wave voltammograms of complex electrode two-step mechanisms.

Item Type:	Teaching Resource
Subjects:	Medical and Health Sciences > Basic medicine Natural sciences > Chemical sciences Natural sciences > Physical sciences
Divisions:	Faculty of Medical Science
Depositing User:	Rubin Gulaboski
Date Deposited:	16 Dec 2021 09:34
Last Modified:	16 Dec 2021 09:34
URI:	https://eprints.ugd.edu.mk/id/eprint/28897

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