Prognostic utility of carotid ultrasound and cardiac SPECT imaging in coronary artery bypass patients

Bosevski, Marijan and Peovska, Irena and Maksimovic, Jelena and Vavlukis, Marija (2006) Prognostic utility of carotid ultrasound and cardiac SPECT imaging in coronary artery bypass patients. Nuclear Medicine Review, 9 (1). pp. 12-17. ISSN 1506-9680

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BACKGROUND: The aim of our study was to evaluate the role
of myocardial perfusion imaging (MPI) and common carotid
artery intima-media thickness (CCA IMT) in the prognosis
of patients with coronary artery disease referred for coronary artery
bypass surgery (CABG) in a newly made prognostic model.

MATERIAL AND METHODS: 63 patients (age 60.36 ± 8.28
years) with angiographically established coronary artery disease
referred for CABG were evaluated for: age, smoking, family
disposition, dyslipidaemia, arterial hypertension, obesity,
diabetes mellitus, previous myocardial infarction and revascularization.
Patients underwent nitrate enhanced Gated SPECT
myocardial perfusion imaging, with 17-segment analysis for calculation
of perfusion scores and viability index. Common carotid
artery IMT was measured by B-mode ultrasound. Patients were
followed for cardiovascular events 12 months after CABG.

RESULTS: The obtained data reported mean values of left ventricular
ejection fraction (LVEF) 46.2 ± 14.4%, viability index
0.76 ± 0.55, SRS 17.76 ± 13.81 and summed nitrate score
12.89 ± 10.36. Ultrasound detected CCA IMT 0.90 ± 0.24 mm, with increased value in 67.2% and presence of carotid plaques
in 27.1% of pts. We registered 14 events and 8.8% mortality rate.
Multiple regression modelling showed bilateral carotid plaque
presence as a predictor of total events. Viability index and CCA
IMT have been found as independent death predictors.

CONCLUSIONS: Myocardial perfusion viability index and CCA
IMT are predictors, independently associated with prognosis
of patients referred for CABG.

Item Type: Article
Subjects: Medical and Health Sciences > Clinical medicine
Divisions: Faculty of Medical Science
Depositing User: Marija Vavlukis
Date Deposited: 29 Jun 2015 14:31
Last Modified: 29 Jun 2015 14:31

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