Phytolacca Americana L: An ethnopharmacological and toxicological review

Bauer, Biljana and Kavrakovski, Zoran and Kostik, Vesna (2013) Phytolacca Americana L: An ethnopharmacological and toxicological review. In: International conference on natural products utilization from plants to pharmacy shelf (ICNPU), 3-6 Nov 2013, Bansko, Bulgaria.

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Phytolacca Americana L. has been used in traditional medicine for treatment of emetic and cathartic properties, dyspepsia and especially for chronic rheumatism. Pokeberries commonly nowadays are used in our country for preparing a remedy in rakia for resolving problems with circulation, cholesterol, metabolism disorders etc. also, pokeberries are often used for healing children’s smallpox. Therefore, there is an increased necessity of an ethnopharmacological and toxicological review of Phytolacca Americana, because it is well known for for it’s toxicity. The work reviews and analysis the traditional use, biological activities with the corresponding chemical constituents, and the toxicological data on the various plant parts. Data regarding Phytolacca Americana was collected using electronic database and library search from selected peer-reviewed articles. Additional information on traditional use and botany was obtained from published books. Phytolacca Americana has been used in northern African, American and southern European traditional medicine. The review encompasses antibacterial the antibacterial usage of poke flowers from Slavic people against abdominal typhus in the seventh century. Turks in the middle ages prepared “krmas madjun”, remedy from poke with grape syrup against fever. Some anti-cancer and anti-viral research has been reported on this perennial herb. The leaves and the roots are especially toxic, the berries much less so, because of their content of phytolaccatoxin and related triterpenes. Intoxications generally arise from eating uncooked leaves in salads or mistaking the roots for parsnips or horseradish. Oral intake of small quantities of raw pokeberries can result in serious disorders of gastrointestinal tract accompanied by weaken respiration and pulse.

Item Type: Conference or Workshop Item (Poster)
Subjects: Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Medical Science
Depositing User: Vesna Kostik
Date Deposited: 26 Jan 2015 11:41
Last Modified: 26 Jan 2015 11:41

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