Adverse effects of circadian disruption

Rodenburg, Wendy and Jansen, Eugene and Ruskovska, Tatjana and Kamcev, Nikola and Velickova, Nevenka (2013) Adverse effects of circadian disruption. [Project] (Unpublished)

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The general aim of this project is to investigate whether working in night shifts leads to chronic health effects via disturbance of the physiological circadian rhythm. Experimental studies carried out at RIVM are aimed at unravelling hormonal and circadian gene expression changes in mice with disturbed day/night rhythm. We aim to develop biomarkers that can, at early time points, predict adverse effects of circadian rhythm disturbances. Moreover, the effect of different shift work schedules on these predictive biomarkers will be analyzed.

Item Type: Project
Subjects: Medical and Health Sciences > Clinical medicine
Divisions: Faculty of Medical Science
Depositing User: Tatjana Ruskovska
Date Deposited: 10 Mar 2014 14:51
Last Modified: 10 Mar 2014 14:51

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