Grune, Tilman and Baron, Caroline and Ruskovska, Tatjana (2010) Chemistry of non-enzymatic protein modification - modulation of protein structure and function. [Project]
Full text not available from this repository.Abstract
Descriptions are provided by the Actions directly via e-COST.
The complexity of human life arises from some twenty thousand genes, and results due to alternative splicing mechanism in approx. 100000 proteins. By posttranslational modifications these proteins are converted into an array of some 1.5 million different functional entities. Interestingly, this conversion can either be enzymatically controlled and regulated, or may have an apparently random aspect due to non-enzymatic reactions. Proteins undergo a wide array of non-enzymatic post-translational modifications. Such modifications of proteins are often determined by their environments, their structural features and by a number of protecting structures, and also by free radicals generated in their vicinity. Non-enzymatic protein modifications are, therefore, not random, but occur in a non-regulated manner and depend largely on the protein and its environment.
| Item Type: | Project |
|---|---|
| Subjects: | Medical and Health Sciences > Basic medicine Natural sciences > Biological sciences Natural sciences > Chemical sciences Medical and Health Sciences > Clinical medicine |
| Divisions: | Faculty of Medical Science |
| Depositing User: | Tatjana Ruskovska |
| Date Deposited: | 27 Feb 2014 13:08 |
| Last Modified: | 21 Jan 2020 12:38 |
| URI: | https://eprints.ugd.edu.mk/id/eprint/9346 |
Actions (login required)
 |
View Item |