Influence of Hyaluronic Acid in Periodontal Tissue Regeneration

Radojkova-Nikolovska, Vera and Popovska, Mirjana and Minovska, Ana and Belazelkovska, Zlatanka (2013) Influence of Hyaluronic Acid in Periodontal Tissue Regeneration. Balkan Journal of Stomatology, 17 (2). pp. 61-64. ISSN 1107-1141

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Hyaluronic acid is a high molecular weight polysaccharide
- glycosaminoglycan, which plays a vital role in the functioning of
extracellular matrices, including those of mineralized and non-mineralized
periodontal tissues. Hyaluronic acid is also important because of its
numerous actions in the mechanisms associated with inflammation and the
wound healing process.
Hyaluronic acid has been identified in all periodontal tissues in
varying quantities, being more prominent in the non-mineralized tissues,
such as gingiva and periodontal ligament, compared to mineralized tissues,
such as the cement and alveolar bone. Preliminary evidence suggests that
hyaluronic acid is a very promising candidate as a mediator of periodontal
tissue regeneration and periodontal disease treatment, by promoting a
rapid remission of symptoms, not only to the marginal gingiva, but also to
the deeper seated periodontal tissues. However, further researches for the
therapeutic effects of hyaluronic acid in periodontal disease are essential for
realization of true benefits of hyaluronic administration in periodontal tissue
Keywords: Hyaluronic Acid; Gingival Inflammation; Periodontal Disease; Periodontal

Item Type: Article
Subjects: Medical and Health Sciences > Basic medicine
Medical and Health Sciences > Clinical medicine
Medical and Health Sciences > Health biotechnology
Medical and Health Sciences > Health sciences
Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Medical Science
Depositing User: Ana Minovska
Date Deposited: 03 Feb 2014 10:40
Last Modified: 12 Mar 2015 13:59

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