The role of Gastroesophageal reflux disease questionnaire in the Republic of Macedonia

Grivceva Stardelova, Kalina and Popova, Roza and Joksimovic, Nenad and Deriban, Gjorgji and Zdravkovska, Milka and Serafimoski, Vladimir (2012) The role of Gastroesophageal reflux disease questionnaire in the Republic of Macedonia. Contributions, Sec. Biol. Med. Sci., MASA, 33 (2). pp. 73-84. ISSN 0351–3254

[thumbnail of Contribution_MANU_so Grivceva-Stardelova 2012.pdf]
Contribution_MANU_so Grivceva-Stardelova 2012.pdf

Download (287kB) | Preview


The aim of the study: Gastroesophageal reflux disease is a common disease with a multifactorial pathogenesis. Our aim was to analyse the role of the Gastroesophageal Disease Questionnaire in diagnosing reflux disease in the population
of the Republic of Macedonia.
Methods: The questionnaire on the severity of the symptoms related to GERD was used. An evaluation of the distal portion of the oesophagus was carried out in all patients with positive questionnaire results. All mucosal injury was classified by the Los Angeles criteria (LA).
Results: 642 patients were included. 58.73% females, with an average age of 37.5 ± 8.2. Females had a higher BMI than males 26.8 ± 4.1 vs. 24.9 ± 3.8 p < 0.001. Of the total number of examinees (642 patients), in those with erosive reflux disease and also in those with nonerosive reflux disease, as shown respectively in endoscopy, the sensitivity
of the RDQ was 100%, and the specifity was 0%. The100 sensitivity means that the questionnaire verified/diagnosed patients with erosive reflux disease with 100% certainty.
Conclusions: Results were found in some studies comparing the positive Reflux Disease Questionnaire and the level of erosive esophagitis (LA classification). This study provides evidence that the RDQ represents a viable instrument for assessing symptom severity and response to treatment in clinical trials of patients with GERD, but in patients with a high score, endoscopic evaluation should not be excluded.
Key words: Gastroesophageal reflux disease (GERD), Reflux Disease Questionnaire, Upper Endoscopy.

Item Type: Article
Subjects: Medical and Health Sciences > Basic medicine
Medical and Health Sciences > Health sciences
Divisions: Faculty of Medical Science
Depositing User: Milka Zdravkovska
Date Deposited: 27 Jan 2014 11:09
Last Modified: 27 Oct 2014 13:25

Actions (login required)

View Item View Item