Pavlovska, Gorica and Darkovska-Serafimovska, Marija and Nestorovska-Gjosevska, Biljana (2011) Comparative examination of the speed of release of Pyridoxin HCL of vitamin B6 tablets á 20 mg. In: 2nd International Congress, Engineering, Ecology and Materials in the Processing Industry, 2011, Jahorina.
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Abstract
Of commercial reasons, Vitamin B6 20 mg tablets which are produced in Radovis were
needed to be produced in Skopje. In order to get licenses for the production of the new location
was necessary to carry out a confirmation of the existing by technology. To this end was made
comparison to the more parameters (appearance, weight, strength, dimensions, fragility,
disintegration, contents, uniformity of content and solubility) of tablets produced in both
locations. In order to confirm the technology was needed to compare the solubility of the two
products in three different media (0.1 M HCl with pH=1.2, acetate buffer with pH=4.5 and
phosphate buffer with pH=6.8). Liberation of HCl was monitored pyridoxine in 12 tablets of the
old site and 12 tablets of the new location, in three intervals of Solubility of tablets in all three
media. It is made statistical processing of the received data confirming the transfer of
technology.
| Item Type: | Conference or Workshop Item (Poster) |
|---|---|
| Subjects: | Engineering and Technology > Medical engineering |
| Divisions: | Faculty of Medical Science |
| Depositing User: | Marija Darkovska-Serafimovska |
| Date Deposited: | 24 Oct 2013 08:13 |
| Last Modified: | 24 Oct 2013 08:13 |
| URI: | https://eprints.ugd.edu.mk/id/eprint/7700 |
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