Velickova, Nevenka and Nikolov, Vlatko and Sterjovska-Aleksovska, Andrijana and Sumanov, Gorgi (2013) The role of alpha-fetoprotein (AFP) in prenatal screening. 3rd Congress of Gynecologists and Obstetricians of Macedonia with International Participation-Book of Lectures and Abstracts. ISSN 978-9989-37-028-1
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Abstract
Introduction: AFP is encoded by the AFP gene, located on the q-arm of chromosome 4 (4q25). AFP levels increase during pregnancy. At the end of the 1-st trimester, fetal AFP levels decrease. Normal adult levels are usually achieved by 8 to 12 months of age. In pregnancy, AFP is analyzed from maternal blood or amniotic fluid as a screening test for chromosomal abnormalities, as principally increased in open neural tube defects and decreased in Down syndrome.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | alpha-fetoprotein, prenatal screening, chromosomal abnormalities, PRISCA software |
| Subjects: | Medical and Health Sciences > Clinical medicine |
| Divisions: | Faculty of Medical Science |
| Depositing User: | Andrijana Sterjovska Aleksovska |
| Date Deposited: | 24 Oct 2013 14:26 |
| Last Modified: | 24 Oct 2013 14:26 |
| URI: | https://eprints.ugd.edu.mk/id/eprint/7657 |
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