Elevated blood markers 1 year before manifestation of malignant glioma

Gartner, Wolfgang and Ilhan, Aysegul and Neziri, Dashurie and Base, Wolfgang and Weissel, Michael and Wohrer, Adelheid and Heinzl, Harald and Waldhor, Thomas and Wagner, Ludwig and Preusser, Matthias (2010) Elevated blood markers 1 year before manifestation of malignant glioma. Neuro-Oncology, 12 (9). pp. 1004-1008.

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We detected distinct plasma concentration profiles of
S100B, neuropeptide Y, and secretagogin in 3 of 191
patients enrolled in a previous study investigating
brain-tissue–related markers in the blood of patients
with atrial fibrillation. Intriguingly, 2 of these 3 patients,
both of whom were without neurological symptoms at
the time of blood sampling, were diagnosed with malignant
glioma (MG) approximately 1 year later. To our
knowledge, this is the first report indicating that distinct
blood biomarker profiles may be detected long before
clinical manifestation of MG.
Keywords: biomarker, blood, glioma, neurooncology.

Item Type: Article
Uncontrolled Keywords: Biomarker, blood, glioma, neurooncology.
Subjects: Medical and Health Sciences > Basic medicine
Medical and Health Sciences > Clinical medicine
Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Medical Science
Depositing User: Biljana Kosturanova
Date Deposited: 05 Mar 2013 15:45
Last Modified: 05 Mar 2013 15:45
URI: https://eprints.ugd.edu.mk/id/eprint/5744

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