Association of tumor necrotisation factor alpha with multivessel coronary disease in patients with acute coronary syndrome

Acute coronary syndrome (ACS) represents a clinical syndrome, which could manifest with or without changes
in the electrocardiogram and with or without elevated cardiac biomarkers. ACS comprises of unstable angina
and myocardial infarction with or without ST segment elevation. Depending on the presence of these signs, the
treatment method for these patients is planned. In addition to the well-established cardiac biomarker troponin,
tumor necrosis factor alpha can also be included in the diagnosis, as independent or in combination with the former
for better diagnosis and creating a treatment plan in future cardiac events. In our study, we aimed to demonstrate
the association between serum TNF-α levels and angiographic prevalence of atherosclerosis in patients with acute
myocardial infarction undergoing coronary angiography and subsequent percutaneous coronary intervention.
According to the results of our study, it can be seen that serum levels of TNF-α are correlated with the occurrence
of acute myocardial infarction and higher values of TNF-α suggest greater involvement of the coronary arteries
by atherosclerosis.