Giant Condyloma Acuminatum of Busche-Lowenstein: A Case Report

Buschke-Löwenstein tumor is a rare, slow-growing tumor that may arise from a pre-
existing condylomatous lesion and has exophytic, cauliflower-like, or papillomatous growth
pattern.
These tumors are associated with low-risk human papillomavirus infection, most
commonly types 6 or 11. They predominantly occur in men in the anogenital region, and are
associated with immunodeficiency. The treatment is controversial, but the greatest success has
been observed with “cold knife” surgical resection with clear margins.
We present the case of a 42-year-old woman with a tumor in the anogenital region that
grew progressively over the course of 6 months. The giant condyloma acuminatum covered most
of the labia majora of the vulva in a continuous pattern. Multifocal condylomas were observed
both at the vaginal introitus and at the lateral aspect of the primary tumor.
The patient was tested and had no other sexually transmitted infections. After adequate
preoperative preparation, a wide partial vulvectomy was performed. The postoperative course was
uneventful.
Adequately planned surgery remains a treatment of choice for patients with giant
condylomas.
Keywords: giant condyloma, vulva, low-risk human papillomavirus,