Ovarian dysgerminoma in pregnancy

Petrova, Deva and Kubelka-Sabit, Katerina and Trajkova, Kornelija and Jasar, Dzengis (2023) Ovarian dysgerminoma in pregnancy. Academic Medical Journal, 3 (3). pp. 108-115. ISSN 26713853

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Abstract

Dysgerminoma is a very rare germ cell tumor of the ovary. It constitutes about 1% of all germ cell malignancies and accounts for 1-5% of all ovarian malignancies in the first two decades of life. Approximately 80% of cases are reported in patients younger than 30 years of age (mean age: 21 years), whereas 75% of women with dysgerminomas present with stage I of the disease. Ovarian tumors generally remain asymptomatic, until they are discovered due to their large size or related complications.Dysgerminomas can occur in pregnant women. Тhe most commonly used diagnostic methods for ovarian tumors in pregnancy are ultrasound and magnetic resonance, not usingradiationforensuring safety of the fetus. Several factors have influence on treatment decisions such as: gestational week of the pregnancy, patient’s expectations, stage of the disease, influence of the diagnostic methods for assessing the stage of the disease on the fetus, as well as the reproductive history of the patient. In stage I of thedisease, fertility sparing surgery with unilateral salpingo-oophorectomy can be performed if the patient wants to preserve fertility. No chemotherapy is required for stage I tumors, unless recurrenceoccurs (9.2% cases).We present a case of dysgerminoma inapregnant patient, treated with unilateral salpingo-oophorectomy. After two years of follow-up, the patient remained free of disease.

Item Type: Article
Subjects: Medical and Health Sciences > Basic medicine
Medical and Health Sciences > Clinical medicine
Divisions: Faculty of Medical Science
Depositing User: Katerina Kubelka-Sabit
Date Deposited: 04 Feb 2026 10:29
Last Modified: 04 Feb 2026 10:37
URI: https://eprints.ugd.edu.mk/id/eprint/37624

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