Prevention of clinical outcome after impacted third molar surgery in correlation with blood fibriolytic activity

Dimova, Cena (2012) Prevention of clinical outcome after impacted third molar surgery in correlation with blood fibriolytic activity. Revista Romana de Medicina Dentara, 15 (1). pp. 24-36. ISSN 1841-6942

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Abstract

The aim was to investigate how impacted third molar surgery, as psychophysical and operative trauma; influence the response of blood fibrinolytic system. Examined group included 50 healthy subjects with impacted third molars and 45 subjects, blood donors, as a control group. Influence of the operative interventions over parameters of blood fibrinolytic system (t-Pa and PAI-1) were examined prior the procedures and immediately after. Values of blood pressure and pulse were notified to evident physical reflections of the stress. Clinical outcome after first, second and seventh day included changes like edema, hematoma, pain and dry socket. Impacted third molar surgery, as a stress factor, had influence and affects the fibrinolysis through the effect upon the pro-activators and inhibitors of the fibrinolytic system, and the severity of the clinical outcome after operative third molar surgery. Parameters of fibrinolytic system - t-PA and PAI-1 can be the most sensitive markers of reaction to oral surgical stress.

Key words: impacted third molar, oral surgery, fibrinolytic system, stress.

Item Type: Article
Subjects: Medical and Health Sciences > Basic medicine
Medical and Health Sciences > Clinical medicine
Medical and Health Sciences > Health sciences
Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Law
Depositing User: Cena Dimova
Date Deposited: 13 Dec 2012 10:52
Last Modified: 30 Sep 2013 10:49
URI: https://eprints.ugd.edu.mk/id/eprint/3551

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