Application of voltammetric methods in electrochemical analyzes of cannabinoids

Aleksandrov, Mihail and Maksimova, Viktorija (2024) Application of voltammetric methods in electrochemical analyzes of cannabinoids. In: 27th Congress of SCTM, Ohrid.

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Abstract

The advantage of voltammetric analysis is rapid, sensitive and inexpensive
methods contributed to their versatile applications: detection of cannabinoids in
biological samples, quality control of cannabis product and analysis of their
antioxidant properties.
A carbon-based electrode modified by initial electrodeposition of Δ9-
tetrahydrocannabinol (THC) has been established to enhance the affinity of the
examined THC molecules to the sensing electrode surface. Amplified square-wave
voltammetry (SWV) signal contributed to its application in detection of THC in
artificial or real saliva samples.1 SWVmethod for detection of cannabinoids in food
products has been developed based on voltammetry of immobilized microparticles
of cannabinol (CBN) and cannabidiol (CBD) at paraffin-impregnated graphite
electrode. Cannabinoids have exhibited net peak potentials at 0.538 V and 0.556
V, for CBN and CBD respectively, attributed to electro-oxidation of a phenolic
group to a phenoxy radical.2 Cyclic voltammetry and differential pulse voltammetry have been utilized in examination of the antioxidant properties of
isolated cannabinoids or Cannabis extract.
Although there are some challenges in practical application of these methods, analysis in forensic purposes and development of electrochemical
sensors for detection of THC in biological samples have been deeply investigated and improved, nowadays.

Item Type:	Conference or Workshop Item (Poster)
Subjects:	Natural sciences > Chemical sciences Medical and Health Sciences > Other medical sciences
Divisions:	Faculty of Medical Science
Depositing User:	Viktorija Maksimova
Date Deposited:	11 Dec 2024 09:01
Last Modified:	11 Dec 2024 09:01
URI:	https://eprints.ugd.edu.mk/id/eprint/35193

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