Diagnostic discrepancy between dermoscopic and histopathological findings in non-melanoma skin cancer, correlation with serum lipids

Petrovska, Lidija and Ruskovska, Tatjana (2024) Diagnostic discrepancy between dermoscopic and histopathological findings in non-melanoma skin cancer, correlation with serum lipids. In: 2nd Biomedicine and Health PhD Students Congress "Science and us", 16-18 May 2024, Rijeka, Croatia.

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Abstract

INTRODUCTION: Non-melanoma skin cancer (NMSC) is the most common cancer in Caucasians. Non-melanoma skin cancer includes basal cell and squamous cell carcinoma with corresponding clinical and histological subtypes. Basal cell carcinoma (BCC) accounts for 75% of cases and is a slow-growing, locally invasive, epidermal tumor with a metastatic rate of <0.1%. Cutaneous squamous cell carcinoma (SCC) is the second most common skin cancer, with an increasing incidence in recent decades. Only about 2% of SCCs are lethal, while the majority of SCCs have a generally favorable prognosis. In both BCC and SCC, mortality is low, but morbidity is high, leading to a significant burden on the healthcare system. The gold standard in establishing the diagnosis still remains the histopathological finding, but there are diagnostic methods that allow for almost precise establishment of the diagnosis, the selection of an appropriate therapeutic approach, which is of great importance for patients if we take into account that the main localization of tumors are the head and the neck.
OBJECTIVES OF THE STUDY: The main objective of the research is to determine the discrepancy between dermoscopy and histology in establishing the diagnosis of NMSC, as well as the influence of serum lipids on the development of NMSC.
MATERIALS AND METHODS: Our research is prospective, observational. It is planned to include about 100 patients with histopathologically proven non-melanoma skin cancer. The subjects will be people with non-melanoma skin cancer who will undergo a clinical and dermoscopic examination.
RESULTS: In this work, we describe three cases of patients with skin tumors, in which a clinical, dermoscopic examination, pathohistological verification of changes, as well as analysis of serum lipids, measurement of glycemia, weight, height, waist circumference and blood pressure. In these patients, the dermoscopic diagnosis corresponds to the pathohistological findings. Dermoscopic evaluation helps in recognizing specific features that guide dermatologists towards early detection, accurate diagnosis and appropriate management of NMSC.

Item Type:	Conference or Workshop Item (Poster)
Subjects:	Medical and Health Sciences > Clinical medicine
Divisions:	Faculty of Medical Science
Depositing User:	Tatjana Ruskovska
Date Deposited:	16 Aug 2024 09:24
Last Modified:	16 Aug 2024 09:24
URI:	https://eprints.ugd.edu.mk/id/eprint/34527

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