Urothelial Carcinoma of Upper Renal Calyces Following Pyelolithiasis: A Case Report

Sofronievska, Maja and Petrovska, Tanja and Radulovska, Jasminka (2024) Urothelial Carcinoma of Upper Renal Calyces Following Pyelolithiasis: A Case Report. In: International Case Report Congress, 5-7 March 2024, Skopje. (Submitted)

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Abstract

Aim: Upper tract urothelial carcinoma (UTUC) is rare but when present more common in the renal calyces than in the ureter. Kidney stone infections and chronic inflammation raise the risk of this carcinoma. Pyelolithiasis with gross hematuria presented in this report is susceptible to misinterpretation in the absence of a comprehensive clinical and imaging diagnostic evaluation particularly in patients with contraindications for some diagnostic procedures.
Case report: We report a 52-year-old female patient who has experienced irregular gross hematuria and flank pain for several years. A pyelocaliceal kidney stone with left-sided upper pole calyceal dilatation was identified by a non-contrast CT scan due to the patient`s iodinated-contrast allergy and further magnetic resonance imaging (MRI) revealed tumor mass on the inner surface of the dilated calyces. A laparoscopic radical nephroureterectomy was performed and a histopathological assessment revealed a high-grade urothelial neoplasm in the upper calyx (pTa). The patient was regularly followed up for five years without disease relapse.
Conclusion: Chronic irritation of kidney stones with or without dilatation must be thoroughly evaluated to rule out urothelial carcinoma of the renal pelvis and calyces. When there is a high suspicion of tumor lesions, magnetic resonance imaging (MRI) is a more reliable diagnostic method than non-contrast CT urography if contrast injection is contraindicated.

Item Type:	Conference or Workshop Item (Poster)
Subjects:	Medical and Health Sciences > Clinical medicine
Divisions:	Faculty of Medical Science
Depositing User:	Maja Sofronievska
Date Deposited:	15 Apr 2024 11:19
Last Modified:	15 Apr 2024 11:19
URI:	https://eprints.ugd.edu.mk/id/eprint/34023

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