Impact of symptom severity score and type of treatment on quality of life in patients with benign prostatic hyperplasia

Sofronievska Glavinov, Maja and Ivcev, Jovan and Stojanoski, Ivica (2022) Impact of symptom severity score and type of treatment on quality of life in patients with benign prostatic hyperplasia. Knowledge – International Journal, 55 (4). pp. 521-526. ISSN 2545 – 4439

Text KNOWLEDGE Repositorium.pdf - Published Version Download (1MB)

Abstract

Benign prostatic hyperplasia (BPH) is the fourth most common disease in the male population aged over
50 years which results in lower urinary tract symptoms (LUTS). These symptoms lead to affect patients' quality of
life (QoL) differently. Quality of life (QoL) refers to the subjective perception of a patient`s well-being in terms of
physical, psychological, and socioeconomic aspects. Aging and worsening LUTS/BPH are contributing factors to
decreased QoL. Several medicament options that include alpha-blockers and 5 alpha-reductase inhibitors as a "gold"
standard, are available for LUTS/BPH treatment. This paper aims to evaluate the effects of pharmacological
treatments used to treat LUTS /BPH in daily practice and to allow a comparison of results between treatments. We
evaluated 250 patients with BPH using the International Prostate Symptom Score (IPSS) questionnaire, including
the eighth question on quality of life concerning the severity of symptoms and the type of drug therapy with which
they were treated. When analyzing the results, we concluded that patients with less pronounced symptoms of the
disease have a better quality of life (p<0.05), while those patients with more severe symptoms and those who have
the appearance of side effects from the therapy have a worse quality of life. (p<0.05). In conclusion, we provide
additional evidence of the impact of two different medicament strategies for BPH treatment on patients' QoL to help
further inform decision-making regarding treatment strategies in this patient population. A holistic approach is
needed in the management of BPH, leading to better QoL in BPH patients.
Keywords: BPH, lower urinary tract symptoms, quality of life

Item Type:	Article
Subjects:	Medical and Health Sciences > Clinical medicine
Divisions:	Faculty of Medical Science
Depositing User:	Ivica Stojanoski
Date Deposited:	20 Feb 2024 12:43
Last Modified:	20 Feb 2024 12:43
URI:	https://eprints.ugd.edu.mk/id/eprint/33678

Actions (login required)

View Item