Influence of non-HDL-C levels on carotid intima-media thickness in healthy individuals and patients with co-morbidities

Chamovska Sheshoska, Hristina and Vasileva Koleski, Katerina and Milachikj, B and Velkoska Nakova, Valentina (2023) Influence of non-HDL-C levels on carotid intima-media thickness in healthy individuals and patients with co-morbidities. Електронското списание за кардиоваскуларна медицина, 7. pp. 8-10.

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Abstract

Aim: To assess the influence of lipoproteins particularly non-HDL-C levels on cIMT in healthy individuals and patients with co-morbidities.
Material and methods: Lipid parameters of 72 patients, divided into two groups were analyzed. The first group included healthy individuals who come for regular check-up without any previous pharmacologic treatment including statins. And, in the second group were patients with
co-morbidities diagnosed and treated in our hospital in the last month, all previously and currently treated with statins. Ultrasound examination on the carotid arteries was performed in all patients.
Results: Statistically significant differences between the groups were in the following variables: age, sex, systolic and diastolic blood pressure, cIMT, carotid stenosis, total cholesterol, triglicerides, HDL, and non-HDL-C. In the healthy group non-HDL-C have statistically significant
positive correlation with age and cIMT (r= 0.442 and r=0.755, p<0.01, respectively), and in the co-morbidity group with diastolic blood pressure and carotid stenosis (r=0.403, p=0.015, and r= 0.332, p=0.048, respectively). Only in the co-morbidity group, age, systolic blood pressure, total cholesterol, non-HDL, and triglicerides have an independent effect on carotid intima media thickness, and systolic and diastolic blood pressure have an independent effect on the carotid stenosis.

Item Type:	Article
Subjects:	Medical and Health Sciences > Clinical medicine
Divisions:	Faculty of Medical Science
Depositing User:	Valentina Velkovska
Date Deposited:	02 Feb 2024 12:58
Last Modified:	02 Feb 2024 12:58
URI:	https://eprints.ugd.edu.mk/id/eprint/33374

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