Krstevska, Brankica and Mishevska, Sasha Jovanovska and Velkoska Nakova, Valentina and Bitoska, Iskra and Guceva, Nevenka Laban and Ahmeti, Irfan and Markovic, Snezana and Todorova, Biljana and Mladenovska, Ivana (2023) Assessment of Prevalence and Risk Factors for Diabetic Retinopathy in Patients with Type 1 and Type 2 Diabetes Examined at a Tertiary Care. PRILOZI, 44 (2). pp. 23-30. ISSN 1857-8985
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Abstract
Introduction : Diabetic retinopathy (DR) is a microvascular complication of diabetes mellitus and the leading cause of visual impairment and blindness. The aim of the study was to estimate and compare the prevalence of DR and to determine an association between DR and systemic risk factors in hospitalized type 1 (DMT1) and type 2 (DMT2) diabetic patients.
Material and methods : We analyzed 260 patients with diabetes, 43 with DMT1 and 217 with DMT2. The following data were collected: age, gender, type and duration of diabetes, glycemic control, blood pressure, estimated glomerular filtration rate, ophthalmologic examinations and routine biochemical parameters.
Results : Out of the total number of 260 patients, 77 (29.6%) had non-proliferative DR (NPDR), 21 (8.1%) had proliferative DR (PDR), 29 (11.1%) had diabetic macular edema (DME), and 69 (23.5%) had diabetic cataracts. Forty-three (16.5%) patients were previously diagnosed with DMT1 and 217 (83.5%) with DMT2. The duration of diabetes was not significantly longer in DMT1 (12.8±11.2 years) in comparison to DMT2 (11.07±8.1 years). The prevalence of NPDR and PDR did not differ statistically in either groups. DME was more prevalent in DMT2 than in DMT1 (P<0.05). Diabetic cataract was found in 26.7% vs. 6.7% of patients with DMT2 and DMT1, respectively (p<0.01). The duration of diabetes significantly correlated with NPDR and PDR in DMT1 (r=o.31, p<0.05; r=0.55, p<0.001, respectively). In DMT2, significant correlations were found between the duration of diabetes and cataract, NPDR, PDR and DME (r=0.31, p<0.001; r=0.43 p<0.01, r=0.16 p<0.05 and r=0.20 p<0.01, respectively). Fasting plasma glucose (FPG) significantly correlated with PDR (r=0.258, p<0.05), while HbA1c with DME (r= 0.15 p<0.05).
Conclusion : The duration of diabetes and hyperglycemia were associated with DR in both types of diabetes.
Item Type: | Article |
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Subjects: | Medical and Health Sciences > Clinical medicine |
Divisions: | Faculty of Medical Science |
Depositing User: | Valentina Velkovska |
Date Deposited: | 02 Feb 2024 12:57 |
Last Modified: | 02 Feb 2024 12:57 |
URI: | https://eprints.ugd.edu.mk/id/eprint/33371 |
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