Covid-19 in children with Down syndrome - case series

Ivanovska, Julija and Nestorov, Hristijan and Popova, Gorica and Chakalarovska, Irena and Petlichkovska, Sandra and Boshkovska, Katerina (2023) Covid-19 in children with Down syndrome - case series. Journal of Morphological Sciences, Vol 6 (2). pp. 93-97. ISSN 2545-4706

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Abstract

Down syndrome (DS) is the most common genetic disease and presents with cognitive
impairment, cardiac and gastrointestinal abnormalities, increased risk of hematological malignancy
and several autoimmune conditions in addition to other miscellaneous clinical conditions
The aim is to show if the comorbidities that children with Down Sy have, were risk factors for
more severe form of COVID-19.
We present three cases of children with Down Sy and COVID-19, with different clinical
features. All of them had good clinical outcome, only the first child had more severe form of Covid 19
with need for oxygen support, longer hospitalization but with good clinical improvement and
withdrawal of the X-ray changes.
Children with Down Sy are always a high-risk group for more severe and prolonged course of
disease, which are partially attributed to defects of the immune system.

Item Type:	Article
Uncontrolled Keywords:	children, Covid- 19, Down syndrome.
Subjects:	Medical and Health Sciences > Clinical medicine
Divisions:	Faculty of Medical Science
Depositing User:	Gorica Popova
Date Deposited:	26 Dec 2023 08:37
Last Modified:	26 Dec 2023 08:37
URI:	https://eprints.ugd.edu.mk/id/eprint/32991

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