Ewing sarcoma

Patients with metastases and recurrent disease still fare poorly, with 5-year survival rates of 20% witch highlights the need for novel chemotherapeutic agents, bisphosphonates and targeted therapy.Ewing's sarcoma has a propensity to metastasize to the lung, bone and bone marrow. This tumor can also involve the CNS with a relatively low incidence – 1-8%.
Prognostic factors that confer poorer outcome are: serum LDH level, axial localization or older age ( > 15 years), size and volume, incomplete or no surgery for local therapy and time of relaps ( < 24 months ).
This is a case report that brings out all of bad prognostic factors associated with disease free survivel and overoll survival.