Evaluation of factors with potential influence on [18F]FDG radiochemical synthesis yield

Cocevska, Maja and Velichkovska, Maja and Atanasova, Marija and Kolevska, Katerina and Jolevski, Filip and Razmoska, Jasmina and Filipovski, Zlatko and Nikolovski, Sasho and Zdraveska Kocovska, Marina and Ugrinska, Ana (2023) Evaluation of factors with potential influence on [18F]FDG radiochemical synthesis yield. Applied Radiation and Isotopes.

Text Chochevska et al. 2023.pdf - Accepted Version Download (572kB)

Abstract

[18F]FDG radiopharmaceutical production is performed with automatic synthesis modules, which enables to
carry out the production process safely, reliably and reproducibly.
This study aimed to investigate the factors which may influence and give inconsistent radiochemical synthesis
yield, as well as common pitfalls in the synthesis process which can occur. We evaluated more than 500 batches
in the overall study.
The results confirmed that irradiation parameter affect the production yield of the final product, also transport
capillary capability and some synthesis factors have an impact on [18F]FDG radiochemical synthesis yield.

Item Type:	Article
Impact Factor Value:	1.6
Subjects:	Medical and Health Sciences > Other medical sciences
Divisions:	Faculty of Medical Science
Depositing User:	Maja Cocevska
Date Deposited:	28 Nov 2023 08:43
Last Modified:	18 Jun 2024 06:54
URI:	https://eprints.ugd.edu.mk/id/eprint/32625

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