Oral signs of adverse drug reactions

Radojkova-Nikolovska, Vera and Nikolovski, Bruno and Dzipunova, Biljana and Toseska Spasova, Natasa and Stojanovska, Vera and Spasovski, Spiro (2023) Oral signs of adverse drug reactions. In: 26th BaSS Congress, 11-14 May 2023, Skopje, North Macedonia.

Text (Oral presentation) 26_BASS Congress OP-126.pdf - Published Version Download (2MB)

Abstract

BACKGROUND: Adverse reactions to drugs are common and may have a variety of clinical presentations in the oral cavity. They are harmful and unintended responses to a medical product. As newer therapeutic agents are approved, it is likely that more adverse drug events will be encountered. The extent of adverse drug reactions is unknown; however, because a lot of them are asymptomatic, many are believed to go unnoticed. Their pathogenesis, especially of the mucosal reactions, is largely unknown and appears to involve complex
interactions between the drug, other medications, the patient’s underlying disease, genetics and lifestyle factors.
AIM: to describe the most common adverse drug reactions that dentists may encounter in daily clinical practice.
MATERIALS AND METHODS: research was done exploring specialized databases PubMed, MEDLINE, EBSCO, Science Direct, and Scopus for the period 2010-2023, by use of MeSH terms: adverse drug reaction, drug-induced reactions, oral manifestation.
RESULTS. The most common oral manifestations were categorized into groups as follows: saliva and salivary gland involvement, soft tissue alterations, hard tissue damage, and non-specific oral conditions.
CONCLUSIONS: Knowledge of adverse drug-induced oral effects helps dental professionals to better diagnose oral disease, administer drugs, and improve patient compliance during drug therapy which may foster a more rational use of drugs.
Keywords: oral cavity, adverse drug reactions, oral signs;

Item Type:	Conference or Workshop Item (Lecture)
Subjects:	Medical and Health Sciences > Basic medicine Medical and Health Sciences > Clinical medicine Medical and Health Sciences > Health biotechnology Medical and Health Sciences > Health sciences Medical and Health Sciences > Other medical sciences
Divisions:	Faculty of Medical Science
Depositing User:	Bruno Nikolovski
Date Deposited:	27 Oct 2023 08:51
Last Modified:	27 Oct 2023 08:51
URI:	https://eprints.ugd.edu.mk/id/eprint/32455

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