Principal Component Analysis to evaluate the stability impact of protein mutations: the case of SARS-CoV-2 K417T mutation

Stojanov, Done and Glavas Dodov, Marija and Velinov, Aleksandar and Nestorovska, Martina (2023) Principal Component Analysis to evaluate the stability impact of protein mutations: the case of SARS-CoV-2 K417T mutation. Macedonian pharmaceutical bulletin, 69 (Sup 1). pp. 273-274. ISSN 1857 - 8969

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Official URL: http://bulletin.mfd.org.mk/volume-69-suppl-1/

Abstract

The severe acute respiratory syndrome CoV-2 (SARS CoV-2), which was initially identified in the Wuhan
Province, China spread worldwide rapidly. The intense
escalation forced the WHO to declare a pandemic with 6.5
million deaths worldwide.
The purpose of this study was to examine and analyze
the impact of K417T mutation upon SARS-CoV-2 S-protein/hACE2 complex stability through the process of
PCA analysis.

Item Type:	Article
Subjects:	Natural sciences > Computer and information sciences Medical and Health Sciences > Health sciences
Divisions:	Faculty of Computer Science
Depositing User:	Done Stojanov
Date Deposited:	28 Sep 2023 09:04
Last Modified:	28 Sep 2023 09:04
URI:	https://eprints.ugd.edu.mk/id/eprint/32265

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