Multidisciplinary approach to management of hypofibrinogenaemia in pregnancy: A case report

Simeonova-Krstevska, Slagjana and Todorovska, Elizabeta and Makarovska-Bojadjieva, Tatjana and Petkovic, Elena and Stojcvevski, Saso and Samardziski, Igor and Spasovski, Saso and Dejanova, Violeta and Grubovic, Radica and Raka, Florije and Jovanovska, Viktorija and Todorovska, Irena and Livrinova, Vesna and Sima, Aneta and Jovcevski, Sasa and Milkovski, Daniel (2020) Multidisciplinary approach to management of hypofibrinogenaemia in pregnancy: A case report. Scripta Medica, 51 (2). pp. 124-128.

[thumbnail of Grubovic R - Scripta Medica 2490-33292002124S.pdf] Text
Grubovic R - Scripta Medica 2490-33292002124S.pdf

Download (153kB)

Abstract

Inherited fibrinogen disorders introduce risk for recurrent abortions, sub-chorionic haematoma, placental abruption and postpartum haemorrhage. This is a case report of a successful pregnancy outcome in a 37-year old woman with hypofibrinogenaemia. She was referred to a coagulation test in the first trimester because of history of preeclampsia and HELLP syndrome in previous pregnancy. Hypofibrinogenaemia was diagnosed with fibrinogen level of 0.7 g/L. During the pregnancy she was regularly monitored for fibrinogen levels and multiple cryoprecipitate concentrates were given. She delivered at 39th gestation week, with elective caesarean section under general anaesthesia. There was one episode of postpartum haemorrhage treated with 2 units of red blood cells, repeated infusions of cryoprecipitate to obtain the level of fibrinogen of 2 g/L. She was discharged on the 6th postpartum day in a good condition. In these disorders levels of fibrinogen should be higher than 1 g/L during pregnancy or 2 g/L in case of caesarean section for successful prenatal and peripartal management.

Item Type: Article
Subjects: Medical and Health Sciences > Clinical medicine
Divisions: Faculty of Medical Science
Depositing User: Rada Grubovik Rastvorceva
Date Deposited: 24 Aug 2022 07:12
Last Modified: 24 Aug 2022 07:12
URI: https://eprints.ugd.edu.mk/id/eprint/30011

Actions (login required)

View Item View Item