Added Value of Modified Anderson–Wilkins Acuteness Score in Prognostication of Patients with Acute Myocardial Infarction

Serafimov, Aleksandar and Taravari, Hajber and Shehu, Enes and Kitanoski, Darko and Miftari, Visar and Georgievska-Ismail, Ljubica and Kedev, Sasko and Vavlukis, Marija (2020) Added Value of Modified Anderson–Wilkins Acuteness Score in Prognostication of Patients with Acute Myocardial Infarction. Open Access Macedonian Journal of Medical Sciences. ISSN 1857-9655

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Abstract

BACKGROUND: Electrocardiogram (ECG) signs on admission can serve as a prognostic marker in patients treated
for myocardial infarction (MI).
AIM: The aim of the study was to determine the predictive role of modified Anderson–Wilkins (MAW) ECG score of
acuteness on the extent of myocardial injury, left ventricular (LV) remodeling, and clinical outcome in patients with
acute MI.
METHODS: Prospective, observational cohort study on patients treated for MI at the University Clinic for Cardiology.
Subjects were analyzed for their demographic, clinical, ECG, LV functional, angiographic variables, course of
treatment, and in-hospital outcome. MAW score was calculated for each patient. Patients were comparatively
analyzed divided in two groups (score <3 and ≥3).
RESULTS: One hundred fifty patients (70% males and 30% females), aged 60.9 years were included in the study.
Sixty-eight patients had MAW score <3 (mean 1.7), and 82 had score ≥3 (mean 3.5), p>0.001. Patients with
ST-segment elevation MI had OR 2.1 (p>0.000), and patients with multiple locations (excluding anterior) had OR 2.1
(p > 0.000) of having MAW score ≥3. They received mechanical reperfusion 1.9 (p = 0.032) times more often. High
MAW score was associated with stress hyperglycemia (OR 2.1; p = 0.032); low potassium (OR 2.8; p = 0.032), lower
creatinine (p = 0.050), and higher NT-proBNP (OR 2.5; p = 0.050). High MAW score was associated with decreased
LV function and increased LV dimensions on the follow-up echocardiography (p = 0.050 and 0.012, respectively).
CONCLUSION: ECG is an important prognostic tool in MI patients. ECG-derived MAW score demonstrates a strong
correlation with stress hyperglycemia, potassium, creatinine, and natriuretic peptides level and can serve as an early
marker of LV remodeling after MI

Item Type:	Article
Subjects:	Medical and Health Sciences > Clinical medicine
Divisions:	Faculty of Medical Science
Depositing User:	Aleksandar Serafimov
Date Deposited:	11 Mar 2022 10:31
Last Modified:	11 Mar 2022 10:31
URI:	https://eprints.ugd.edu.mk/id/eprint/29591

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