Association of adverse pregnancy outcome with the values of serum biomarkers of Quadruple test

Izairi, Pranvera and Velickova, Nevenka (2021) Association of adverse pregnancy outcome with the values of serum biomarkers of Quadruple test. Albanian Journal of Medical and Health Sciences (AJMHS), 57. pp. 1-12. ISSN 2412-6373 / 2413-3892 online

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Abstract

Background: Prenatal test includes prenatal
screening and diagnosis that aims to find different
changes in fetus and mother during the
pregnancy. Prenatal screening is focused in
finding any possible pathology in the wide
population using some noninvasive methods.
The changes of utero-placental blood flow lead to
utero-placental insufficiency, which will be
manifested by pregnancy induced hypertension,
preeclampsia, intrauterine growth retardation
or/and small for gestation age fetus, preterm
birth, etc.
Aim: of this research is to perform a prenatal
screening of serum biomarkers from Quadruple
test in the second trimester of pregnancy, in order
to predict early diagnosis of eventual adverse
pregnancy outcome.
Material and method: This prospective study is
realized in the Special Hospital for Gynecology
and Obstetrics “Mother Theresa”, Skopje, during
the period November 2019 to June 2021. It
includes 673 pregnant women, between 18-23.6
gestational weeks, followed up and monitored till
delivery. We followed up the values of serum
biomarkers from Quadruple test, fetal biometry,
quantity of amniotic fluid and gestational week
and bodily measures of the fetus in delivery.
Statistical processing: It was conducted a
statistical analysis of maternal characteristics in
research group and the group with no adverse
pregnancy, determining the variables which
significantly associate with adverse pregnancy
outcome.

Item Type:	Article
Subjects:	Medical and Health Sciences > Basic medicine Medical and Health Sciences > Clinical medicine
Divisions:	Faculty of Medical Science
Depositing User:	Nevenka Velickova
Date Deposited:	04 Feb 2022 08:51
Last Modified:	23 Aug 2023 09:51
URI:	https://eprints.ugd.edu.mk/id/eprint/29238

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