Yzeiri Havziu, Drita and Gjorgjeska, Biljana and Miftari, Visar and Alili Idrizi, Edita and Alija, Gjylaj and Haxhiu Zaimi, Arlinda and Dauti, Merita and Ahmeti Lika, Sihana and Balazhi, Lulzime (2021) Evaluation a renal function of patients with Medication-overuse headache (MOH). In: 10th International Conference on Business, Technology and Innovation 2021, Oct 29th, 4:00 PM - Oct 30th, 8:00 AM, University for Business and Technology - UBT.
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Abstract
Excessive drug use causes Medication-overuse headache (MOH) which can be manifested of chronic daily headaches, occurring monthly 15 or more days, when the medicament is used redundantly for more than three months. Recent studies concerning the epidemiology of drug-induced disorders suggest that increased risk of nephrotoxicity appears in a group of patients who abuse NSAIDs. The aim is to confirm the early phase of nephrotoxicity in patients with (MOH),were treated with NSAIDs in combination with other drugs (analgesics, triptans and antidepressants) and compared patients treated only with Diclofenac, Piroxicam, Ketoprofen, Paracetamol, Ibuprofen and Celecoxib, Besides conventional markers of renal functioning (serum/urine creatinine determined by Jaffe methods, enzymatic assay for urea serum). Imunoturbodimetric assay for determination of urinary albumin, microalbuminuria and β2-microglobulin will be used. Significant glomerular and tubular damage has been reported, and patients on combination therapy with NSAIDs and other drugs (analgesics, triptans, and antidepressants) have seen more glomerular changes than patients treated with NSAID monotherapy.
Keywords: Medication-overuse headache, Nephrotoxicity, Nonsteroidalantiinflammatory drugs.
| Item Type: | Conference or Workshop Item (Lecture) |
|---|---|
| Subjects: | Medical and Health Sciences > Clinical medicine Medical and Health Sciences > Health sciences Medical and Health Sciences > Other medical sciences |
| Divisions: | Faculty of Medical Science |
| Depositing User: | Biljana Gorgeska |
| Date Deposited: | 24 Jan 2022 08:51 |
| Last Modified: | 24 Jan 2022 08:51 |
| URI: | https://eprints.ugd.edu.mk/id/eprint/28977 |
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