The impact of cognitive functioning on the quality of life in patients with schizophrenia

Memedi, Imran and Miloseva, Lence (2021) The impact of cognitive functioning on the quality of life in patients with schizophrenia. Medical Journal Medicus, 26 (1). pp. 46-52. ISSN 1409-6366 UDC 61.

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Abstract

Introduction: Schizophrenia is an endogenous psychotic disorder with a chronic course. The clinical features of schizophrenia is dominated by positive, negative symptoms, as well as cognitive dysfunction, which affects the quality of life.
Objective: To determine the relationship between cognitive dysfunction and quality of life in patients with first-episode schizophrenia and a chronic course of the disease.
Method: The research involved 37 randomly selected male and female respondents from 18 to 60 years of age who suffer from schizophrenia according to the diagnostic criteria of the International Classification of Diseases - ICD 10. The respondents are divided into two groups. The first group consists of 21 patients with schizophrenia in an acute period of the disease, while the second group consists of 16 patients with chronic schizophrenia treated in the PHI Psychiatric Hospital Skopje-Skopje and the PHI University Clinic of Psychiatry, Skopje. We used the following measuring instruments: the Positive and Negative Syndrome Scale (PANSS), the Schizophrenia Cognition Rating Scale (SCoRS) and the World Health Organization Quality of Life (WHOQOL)-BREF scale. For the statistical data processing, we used the statistical package SPSS version 26 (Statistical Package for the Social Science).
Results: By applying ANOVA we found that the quality of life in acute patients is linearly related with at least one predictor, i.e. F (21) =3.570, sig. =.036, p<.05. In the regression analysis using the t-test we found that there is a significant relationship between the quality of life and the total score of the cognitive functioning obtained by the informer t(21)= -2.582, sig.=0.019, p<.05; while there is no statistically valid relationship between the quality of life and the total score of cognitive functioning obtained by the patient t(21)=1.158, sig.=0.263, p>.01 and between the quality of life and the total score of cognitive functioning obtained by the interviewer t(21)=0.096, sig.=0.925, p>.01. Also by using ANOVA, we found that the quality of life in chronic patients is not linearly related to any predictor,i.e. F (16) =0.840, sig. =.498, p>.05. In the regression analysis using the t-test we also found that there is no relationship between the quality of life and the predictors.
Conclusion: In the course of our longitudinal prospective study, we found that cognitive dysfunction in schizophrenia affects a person’s quality of life, whereby this is evident in the acute phase of the disease. Rehabilitation is focused on building the required skills for everyday life and work in the community and is based on the principles of recovery and empowerment, it encourages the patient’s autonomy by fostering the ability to work and by reducing incapacity –it improves self-confidence, social functioning, and quality of life.

Item Type:	Article
Subjects:	Medical and Health Sciences > Clinical medicine
Divisions:	Faculty of Medical Science
Depositing User:	Lence Miloseva
Date Deposited:	20 Dec 2021 08:26
Last Modified:	20 Dec 2021 08:26
URI:	https://eprints.ugd.edu.mk/id/eprint/28926

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