Characterization of Resveratrol Loaded Nanoparticles-A Review

Drakalska, Elena and Miceva, Dijana and Angelovska, Bistra and Makraduli, Liljana (2021) Characterization of Resveratrol Loaded Nanoparticles-A Review. International Journal of Pharmaceutical Research and Applications, 6 (2). pp. 655-659. ISSN 2249-7781

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Abstract

Resveratrol (3,5,4-trihydroxy-transstilbene) is natural phenol and phytoalexin,
extracted from red grapes, berries and cacao beans
and found also in significant concentration in red
wine. This active compound exhibited potent
pleiotropic, antineoplastic activity without
documented toxicity to normal cells. In addition,
numerous studies reported that resveratrol, as most
researched stilbene, possess numerous healthbenefit properties, such as cardioprotective,
antidiabetic, neuroprotective and chemopreventive.
Regretfully, clinical realization of resveratrol is
restricted due to its poor aqueous solubility (0.05
mg/ml), degradation at physiological pH associated
with extremely low systemic bioavailability. An
intriguing strategy to overcome these limitations is
formulation of resveratrol-loaded nanoparticles
such as nanoemulsions, liposomes and solid-lipid
nanoparticles as platforms for delivery to target
tissues

Item Type:	Article
Subjects:	Medical and Health Sciences > Other medical sciences
Divisions:	Faculty of Medical Science
Depositing User:	Elena Drakalska
Date Deposited:	11 May 2021 09:24
Last Modified:	29 Mar 2024 12:14
URI:	https://eprints.ugd.edu.mk/id/eprint/28062

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