Devitilizing agents in endodontics

Kovacevska, Ivona and Petrovski, Mihajlo and Terzieva-Petrovska, Olivera and Kovacevski, Ivo (2020) Devitilizing agents in endodontics. Macedonian Pharmaceutical Bulletin.

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Abstract

Different types of pulpal inflammation mostly
are presented as a sequel of dental caries. Most of
the general dental practitioners find management of
the inflamed pulp challenging in their routine dental
practice. First step in the mortal endodontic methods
of treatment is positioning of devitalizing
medicament. The devitalizing agents can compose of
formaldehyde, cresol, paraformaldehydeor some
arsenic compounds. These agents can be harmful to
the patients mostly because of their highly toxic,
allergic, carcinogenic and mutagenic/genotoxic
properties.
Toxic devitalizing agents such as arsenic
trioxide and paraformaldehyde were commonly used
in the past to devitalize inflamed pulps when
effective anesthesia could not be obtained . Among these two substances an important role played paraformaldehyde pastes. Paraformaldehyde agents can play role as
disinfectants and can devitalize inflamed pulps when
local anesthesia is ineffective. Despite the clinical
benefits, paraformaldehyde can penetrate through
dentine and is gradually released as formaldehyde.
Formaldehyde released through dentine has a
destructive effect on periodontal and bone tissues.

Item Type: Article
Subjects: Medical and Health Sciences > Health sciences
Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Medical Science
Depositing User: Mihajlo Petrovski
Date Deposited: 31 Jan 2021 18:18
Last Modified: 31 Jan 2021 18:18
URI: https://eprints.ugd.edu.mk/id/eprint/27365

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